Attack on your brain: How autoantibodies against the myelin sheath protein MOG recognize their target
Mai 2021 – Das menschliche Immunsystem erzeugt eine enorme Vielfalt an Antikörpern, die erforderlich sind, um uns vor Krankheitserregern zu schützen. Dabei werden aber auch Fehler gemacht und es kommt zur Bildung von Autoantikörpern, die körpereigene Strukturen angreifen und zum Beispiel rheumatische Erkrankungen oder Entzündungen im Gehirn verursachen.
Outstanding Publication Award for single cell analysis of MS twins
Mai 2021 – Eduardo Beltrán, Lisa-Ann Gerdes and Julia Hansen received the Outstanding Publication Award 2021 for their study on Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis that was published in the Journal of Clinical Investigations. The outstanding publication award is made possible by the generous support of the Rosa Laura and Hartmut Wekerle foundation and recognizes a particularly impactful publication from our insitute. The study impressed the reviewers with the innovative technological approach, the elegant clinical design and the important and novel insights into the immunological alterations that characterize the earliest stages of multiple sclerosis. (Read More...)
Julie Fourneau (Bareyre Lab) awarded with a Wings for Life post-doctoral fellowship
April 2021 – Julie Fourneau from our institute and post-doctoral student in the laboratory of Florence Bareyre has been awarded a 2-years post-doctoral fellowship from the Wings for Life Foundation. During this time, Julie Fourneau will study how immune cells in the spinal cord control axonal wiring following spinal cord injury. Her work should reveal how immune cells contribute to the establishment of correct connectivity in the injured CNS (Read More...)
Franziska Thaler receives funding from the Advanced Clinician Scientist Module of the Munich Cluster for Systems Neurology (SyNergy)
February 2021 – Franziska Thaler from our institute will receive funding from the Advanced Clinician Scientist Module within the framework of the Munich Cluster for Systems Neurology (SyNergy) for her project: B-cell-mediated immune response in GAD-antibody associated neurological disorders“. For this study, Franziska Thaler and her team will focus on the characterization of B cells and autoreactive antibodies in different B-cell compartments on a single cell level. (Read More...)
Collaborative Research Center on Multiple Sclerosis will be funded for 4 more years
February 2021 – The DFG will extend the funding of the transregional CRC 128 „Multiple Sclerosis“ for its third funding period (until mid-2024). In this research initiative Anneli Peters, Edgar Meinl, Naoto Kawakami and Martin Kerschensteiner from our institute work together with colleagues from the TU Munich as well as the universities of Mainz and Münster to investigate initiating, effector and regulatory mechanisms in the disease process. (Read More...)
Valérie Van Steenbergen (Bareyre Lab) awarded with an Alexander von Humboldt post-doctoral fellowship
November 2020 – Valérie Van Steebergen, from our institute and post-doctoral student in the laboratory of Florence Bareyre has been awarded a 2-years post-doctoral fellowship from the Alexander von Humboldt Foundation. During this time, Valérie will study the role of neuronal activity in the shaping of new circuits following CNS injury. Her work should determine whether and how stimulation of activity in nerve cells can drive functional recovery following CNS injuries. (Read More...)
Martin Kerschensteiner elected to the National Academy of Sciences (Leopoldina)
October 2020 – Martin Kerschensteiner, director of the Institute of Clinical Neuroimmunology, has been elected as a member of the German National Academy of Sciences Leopoldina. The Leopoldina orignated in 1652 and now has 1600 members from almost all branches of sience. The mission of the Leopoldina is to represent the German scientific community internationally and provide policy makers and the public with science-based evidence. Martin Kerschensteiner will join the „Sektion“ Neurosciences (Read More...)
Simone Mader (Meinl Lab) receives funding from Novartis to search for new CNS-reactive antibodies
October 2020 – Simone Mader from our institute will receive 40.000 Euro funding for her Oppenheim-Förderpreis application on the “Characterization of CNS-reactive antibodies in multiple sclerosis and related diseases” after internal validation by Novartis. For this study, Simone Mader will focus on patients with multiple sclerosis or similar diseases who present with optic neuritis. Brain-reactive antibodies and B cells will be investigated using novel methodological approaches, in order to identify target antigens. The identification of such autoantibodies is of high diagnostic and therapeutic relevance.